Developer Terms and Conditions The Development Molecular Sensing Models Comparing SCIO with FTIR Spectroscopy

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    We are working on a project where we want to see how the SCIO technique compares with professional spectroscopy techniques like FTIR. We would like to know what you think will  be the  best way to compare these two techniques?


    The reason we ask is because, we find it difficult to put these two techniques against each other. The results from the SCIO scan seem to be projected in a different way as the FTIR results. We know what is presented in the FTIR graphs, but we can’t figure out what is precisely presented in the graphs from the SCIO scans. So what is precisely presented in the graphs from the SCIO scans? which units are used on the x and y axes and at what magnitude.



    TU Delft


    Hi Zjenja!

    Thanks so much for contacting us.

    I will contact you shortly with the information you have requested.

    Warm regards,



    Can we still expect an answer from you guys?


    Dear Zjenja, 

    We have responded to your question via email.

    The ConsumerPhysics Team

    • This reply was modified 8 years, 6 months ago by Ayelet.
    • This reply was modified 8 years, 6 months ago by Admin.



    Can the answer be shared? I am also interested in this.


    Thank you


    Please do share this information as it will be helpful in answering questions from the scientific community in regards to viability and trustworthiness of the SCiO methodology.


    Additionally, what legal disclaimers will be required with any application that is developed? :unsure:

    Hi all,
    Regarding the displayed graphs from SCiO scans:

    X is the wavelength represented in nm (nanometers).
    Y is dependent on the state of the toggle buttons you select.

    Processed (only): Assumes Beer-Lambert model is valid, and transforms the measured signal to be linear with concentration by doing a log transform and adjusting the result for noise and deviations from the model. 


    Normalized (only): Performs normalization of the signal. This is meant to compensate for changing measurement conditions (e.g. varied scanning distances) that typically occur from sample to sample. Y axis still means reflectance but in normalized units instead of raw reflectance.


    Both Processed and Normalized: First assumes Beet-Lambert model (Processed) and then normalizes the results to compensate for differences in the optical path between samples. This is useful, for example, when there is variation in the thickness of the samples.


    Both (log)R))” and Normalized:Similar to Processed and Normalized, uses a more aggressive form of Processed. Adds more noise, but in some cases may be the only way to create a good model.

    Typically, different models and types of samples will require different pre-processing methods. You should both choose the pre-processing method to match your experimental setup and optimize the performance of your model. If you planned and gathered your data correctly, these efforts will coincide.

    As for comparing with other techniques, there is always some difference between devices, especially if you use different pre-processing methods.

    It should be noted that SCiO is a complete system that includes spectrometer, internal illumination source and machine learning algorithms optimized for SCiO. The best way to compare those technique is to try and create chemoemetric models with each technique and evaluate their performance.

    Regarding legal disclaimers, you can visit our Terms & Conditions page at our website here.



    The ConsumerPhysics team

    • This reply was modified 8 years, 6 months ago by Ayelet.
    • This reply was modified 8 years, 6 months ago by Ayelet.

    Hi, I am also trying to convert SCiO spectra to be comparable to a standard FTIR reference library.  Have you had any luck?  I am trying to open the raw SCiO data in Spekwin32, and output as .dx.  Has anyone tried this or any other method?

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